First things first, do not start retinoid therapy if you are pregnant or nursing. If you’re beginning retinoid therapy for the first time or if you’re an expert starting your treatment again after a few months, you’ll want to make sure you are skin ready. Take a break from your exfoliator 2-7 days before -depending on skin sensitivity. Also, make sure you have a daily sunscreen ready, one that you love to apply since SPF protection is vital to the maintenance of treatment progress.